There is setting in winecfg in current version but it have strangely low
maximum limit so it is useless in most cases. This is how I do it. Execute to
make sure that WINE is really closed (if you forgot this step then registry
changes may "magically" disappear):
wineserver -k
Now open registry with your favorite editor. I like nano, but you can use
kwrite or any other you like:
nano ~/.wine/system.reg
Search for "LogPixels" there. You will see something like this:
"LogPixels"=dword:00000060
Change 60 to something more suitable. For example this is what I use with my
two displays (one with resolution 1680x1050 and another one with 1280x1024):
"LogPixels"=dword:00000095
Save the registry. Now you can try to launch notepad to see the result:
wine notepad
If you don't like the result repeat all steps. If you like it then you're
done.
source : http://www.winehq.org/pipermail/wine-users/2007-October/027896.html
source : http://www.winehq.org/pipermail/wine-users/2007-October/027896.html